“Demonstrates how some of the most accomplished and elite scientific gatekeepers may have lied, cheated, squandered trust and endangered lives.” —The Wall Street Journal In this episode of the You Are Not Broken podcast, Dr. Kelly Casperson interviews investigative journalist Charles Piller about his newly released book, 'Doctored,' which delves into the misconduct in Alzheimer's research. They discuss the amyloid hypothesis, the role of whistleblowers, the FDA's controversial drug approvals, and the systemic issues in medical research. Piller emphasizes the importance of scientific integrity and the need for independent oversight in research while also exploring emerging theories in Alzheimer's treatment and the impact of lifestyle factors on prevention. Takeaways The amyloid hypothesis has dominated Alzheimer's research but has significant flaws. Whistleblowers play a crucial role in exposing misconduct in scientific research. The FDA's approval process for drugs can be influenced by industry relationships. Lifestyle factors such as diet and exercise can impact Alzheimer's risk. There is a growing interest in alternative theories for Alzheimer's treatment. AI can assist in detecting research fraud but also poses risks for falsification. Misinformation in health media can lead to public harm and confusion. Independent agencies are needed to investigate scientific misconduct effectively. The scientific community must improve transparency and accountability. There is hope for progress in Alzheimer's research despite current challenges. Sedona in October - only a few slots left: https://www.ascendretreats.com/menopause-and-sexual-health-2025 Order my book "You Are Not Broken: Stop "Should-ing" All Over You Sex Life" Listen to my Tedx Talk: Why we need adult sex ed Take my Adult Sex Ed Master Class: My Website Interested in my sexual health and hormone clinic? Starts 2025. Thanks to our sponsor Midi Women's Health. Designed by midlife experts, delivered by experienced clinicians, covered by insurance. Midi is the first virtual care clinic made exclusively for women 40+. Evidence-based treatments. Personalized midlife care. https://www.joinmidi.com Thanks to our sponsor Sprout Pharmaceuticals. To find out if Addyi is right for you, go to addyi.com/notbroken and use code NOTBROKEN for a $10 telemedicine appointment. See Full Prescribing Information and Medication Guide, including Boxed Warning for severe low blood pressure and fainting in certain settings at addyi.com/pi To learn more about Via vaginal moisturizer from Solv Wellness, visit via4her.com for 20% off your first purchase of any product, automatically applied at checkout. For an additional $5 off, use coupon code DRKELLY5. Learn more about your ad choices. Visit podcastchoices.com/adchoices